| Chief Minister | From | To |
|---|
| M.K.StalinDMK | 07 May 2021 | Present |
| Edappadi K. PalaniswamiAIADMK | 16 Feb 2017 | 06 May 2021 |
| O. PanneerselvamAIADMK | 06 Dec 2016 | 15 Feb 2017 |
| J. JayalalithaaAIADMK | 24 May 2016 | 04 Dec 2016 |
| J. JayalalithaaAIADMK | 23 May 2015 | 23 May 2016 |
| O. PanneerselvamAIADMK | 29 Sep 2014 | 22 May 2015 |
| J. JayalalithaaAIADMK | 16 May 2011 | 27 Sep 2014 |
| M. KarunanidhiDMK | 13 May 2006 | 15 May 2011 |
| J. JayalalithaaAIADMK | 02 Mar 2002 | 12 May 2006 |
| O. PanneerselvamAIADMK | 21 Sep 2001 | 01 Mar 2002 |
| J. JayalalithaaAIADMK | 14 May 2001 | 21 Sep 2001 |
| M. KarunanidhiDMK | 13 May 1996 | 13 May 2001 |
| J. JayalalithaaAIADMK | 24 Jun 1991 | 13 May 1996 |
| President’s rule | 30 Jan 1991 | 24 Jun 1991 |
| M. KarunanidhiDMK | 27 Jan 1989 | 30 Jan 1991 |
| President’s rule | 30 Jan 1988 | 27 Jan 1989 |
| Janaki RamachandranAIADMK | 07 Jan 1988 | 30 Jan 1988 |
| V.R. NedunchezhiyanAIADMK | 24 Dec 1987 | 07 Jan 1988 |
| M. G. RamachandranAIADMK | 10 Feb 1985 | 24 Dec 1987 |
| M. G. RamachandranAIADMK | 09 Jun 1980 | 15 Nov 1984 |
| President’s rule | 17 Feb 1980 | 09 Jun 1980 |
| M. G. RamachandranAIADMK | 01 Jul 1977 | 17 Feb 1980 |
| President’s rule | 31 Jan 1976 | 30 Jun 1977 |
| M. KarunanidhiDMK | 15 Mar 1971 | 31 Jan 1976 |
| M. KarunanidhiDMK | 10 Feb 1969 | 04 Jan 1971 |
| V.R. NedunchezhiyanDMK | 03 Feb 1969 | 10 Feb 1969 |
| C. N. AnnaduraiDMK | 06 Mar 1967 | 03 Feb 1969 |
| M. BakthavatsalamINC | 02 Oct 1963 | 06 Mar 1967 |
| K. KamarajINC | 15 Mar 1962 | 02 Oct 1963 |
| K. KamarajINC | 13 Apr 1957 | 01 Mar 1962 |
| K. KamarajINC | 13 Apr 1954 | 31 Mar 1957 |
| C. RajagopalachariINC | 10 Apr 1952 | 13 Apr 1954 |
| P. S. Kumaraswamy RajaINC | 26 Jan 1950 | 10 Apr 1952 |
| P. S. Kumaraswamy RajaINC | 06 Apr 1949 | 26 Jan 1950 |
| O. P. Ramaswamy ReddiyarINC | 23 Mar 1947 | 06 Apr 1949 |
| Tanguturi PrakasamINC | 30 Apr 1946 | 23 Mar 1947 |
| Governor’s RuleINC | 29 Oct 1939 | 30 Apr 1946 |
| C. RajagopalachariINC | 14 Jul 1937 | 29 Oct 1939 |
| Kurma Venkata Reddy NaiduInterim provisional ministry | 01 Apr 1937 | 14 Jul 1937 |
| Raja of BobbiliJustice Party | 24 Aug 1936 | 01 Apr 1937 |
| P. T. RajanJustice Party | 04 Apr 1936 | 24 Aug 1936 |
| Raja of BobbiliJustice Party | 05 Nov 1934 | 04 Apr 1936 |
| Raja of BobbiliJustice Party | 05 Nov 1932 | 05 Nov 1934 |
| B. Munuswamy NaiduJustice Party | 27 Oct 1930 | 05 Nov 1932 |
| P. SubbarayanUnaffiliated | 04 Dec 1926 | 27 Oct 1930 |
| Raja of PanagalJustice Party | 19 Nov 1923 | 04 Dec 1926 |
| Raja of PanagalJustice Party | 11 Jul 1921 | 11 Sep 1923 |
| A. Subbarayalu ReddiarJustice Party | 17 Dec 1920 | 11 Jul 1921 |
